Dr Hal Brown, Naturopathic Physician
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Patient Testimonials for Prolotherapy PRP and more

What does Prolotherapy treat? an A-Z listing

Naturopathic Integrated Approach to Prolotherapy

Prolotherapy, PRP articles

After Treatment Guidelines


How safe is prolotherapy?

FAQs about Prolotherapy

Acupuncture, Trigger
Points and Prolotherapy

Neural Prolotherapy NPT

a new therapy procedure added to the treatment options for osteoarthritis and chronic joint, ligament and muscle pain.

"Theatre, Cocktail Party Syndrome"
An indication for Prolotherapy

Your back, leg, neck or other pain is worse when standing still, like at a cocktail party. When you go to sit down, there is some relief but if you sit for too long, like in the theatre, the pain returns.  There may only be relief as long as you are active, returning once you rest.


Prolotherapy Articles

New York Times article on Prolotherapy                                        Injections to Kick-Start Tissue Repair

Journal of Practical Pain Management:                                 Prolotherapy for Low Back Pain

Journal of Practical Pain Management:

Prolotherapy for Musculo-skeletal Pain: A primer for pain management physicians on the mechanisms of actions and indications for use. Jan/Feb., 2007

Journal of Practical Pain Management  May, 2007:Prolotherapy for Low Back Pain

 Biomechanics: Sweet Relief: The Scientific Research Behind Prolotherapy / RIT

Journal of Practical Pain Management  July, Aug., 2007 : Prolotherapy for Knee Pain

Dextrose Prolotherapy forUnresolved Neck Pain

In this study, 97 out of 98 patients with chronic neck pain showed substantial improvement in numerous outcome measures. The improvements in these patients continued through follow up—18 months after conclusion of prolotherapy treatments—and demonstrates the efficacy of this treatment modality.

Sports Groin Injuries:

Efficacy of Dextrose Prolotherapy in Elite Male Kicking-Sport Athletes With Chronic Groin Pain Archives of Physical Medicine and Rehabilitation 2005; 86: 697-702
Conclusions: "Dextrose Prolotherapy showed marked efficacy for chronic groin pain in this group of elite rugby and soccer athletes."

Knee Injuries:

Long Term Effects Of Dextrose Prolotherapy For Anterior Cruciate Ligament Laxity
University of Kansas Medical Center, Alternative Therapies, May/June 2003, Vol. 9 No. 3
Conclusions: "Dextrose injection Prolotherapy at 2-3 month intervals resulted in elimination of laxity by machine measure in 10/16 knees in the study population, with statistically significant laxity improvement by 6 injections, sustainable through 3 years with periodic injection."

Knee Arthritis:

X-rays of regeneration of a knee from prolotherapy

Knee Arthritis Study Using Dextrose Prolotherapy
University of Kansas Medical Center, Alternative Therapies, March 2000, Vol. 6, No 2
Conclusions: “… substantial improvements in joint pain, subjective joint swelling, flexion range of motion, and tendency for knee buckling…This study result, coupled with findings of a double-blind study on small joint (finger) OA, indicates that dextrose injection may have broad effectiveness in the treatment of joint and soft tissue...In the meantime Prolotherapy with dextrose should be considered as one of the treatments for OA of knee and ACL laxity.”

Low Back Pain:

Retrospective Case Series on Patients with Chronic Spinal Pain Treated with Dextrose Prolotherapy
Results: 91% of patients reported reduction in level of pain; 84.8% of patients reported improvement in activities of daily living, and 84.3% reported an improvement in ability to work.
Conclusions: “Dextrose prolotherapy appears to be a safe and effective method for treating chronic spinal pain..."

Chronic Pain:

A Systematic Review of Prolotherapy for Chronic Musculo-skeletal Pain
Clinical Journal of Sports Medicine; 15(5):E376, September 2005
Conclusions: “Positive results compared with controls have been reported in nonrandomized and randomized controlled trials."

PRP Regenerative Injection Therapy

Comprehensive Scientific Overview on the Use of Platelet Rich Plasma Prolotherapy (PRP)

PRP Platelet Rich Plasma

Globe and Mail: Injured? Heal yourself with your own blood

Journal of the American Academy of Orthopaedic Surgeons (JAAOS). Early outcomes of PRP appear promising

PRP Prolotherapy used successfully for professional athletes

PRP keeps Hines Ward and Troy Polamalu of the Pittsburgh Steelers  in the game

PRP used by figure skater Patrick Chan, Canadian Olympic Team, B.C. Lions


muscles & ligaments of the
neck and upper back


Vancouver Prolotherapy

Prolotherapy is helpful for what conditions?

The treatment is successful for most types of musculoskeletal pain, including degenerative joint conditions, arthritis, back pain, neck pain, fibromyalgia, sports injuries, yoga overstretching injuries, dislocations, unresolved whiplash injuries, carpal tunnel syndrome, chronic tendonitis, partially torn tendons, ligaments and cartilage, degenerated or herniated discs, TMJ, sciatica.

Prolotherapy also treats most pain conditions:

Hip pain, Knee pain, Ankle pain and foot pain, Wrist pain, Elbow pain, Shoulder pain, Headaches, TMJ (jaw) pain, Post Injury/Trauma Pain, Fibromyalgia, Myofascial conditions, Sports Injuries, Loose Joints, Tendonitis, Post fracture treatment, Rib Pain and more.  In fact any joint, ligament or muscle tendon in the body that is experiencing pain can be treated with prolotherapy.

What is prolotherapy?
First, it is important to understand what the word prolotherapy itself means. "Prolo" is short for proliferation, because the treatment causes the proliferation (growth, formation) of new ligament tissue in areas where it has become weak.

Ligaments are the structural "rubber bands" that hold bones to bones in joints. Ligaments can become weak, overstretched or injured and may not heal back to their original strength, length or endurance. This is largely because the blood supply to ligaments is limited, and therefore healing is slow and not always complete. To further complicate this, ligaments also have many nerve endings and therefore the person will feel pain at the areas where the ligaments are damaged or loose.

Tendons are the name given to tissue which connects muscles to bones, and in the same manner tendons may also become injured, and cause pain.

Prolotherapy uses a dextrose (sugar water) solution, which is injected into the ligament or tendon where it attaches to the bone. This causes a localized inflammation in these weak areas which then increases the blood supply and flow of nutrients and stimulates the tissue to repair itself.

Historical review shows that a version of this technique was first used by Hippocrates on soldiers with dislocated, torn shoulder joints. He would stick a hot poker into the joint, and it would then miraculously heal normally. Of course, we don’t use hot pokers today, but the principle is similar—get the body to repair itself, an innate ability that the body has.

How long will it take to complete a course of treatments?
The response to treatment varies from individual to individual, and depends upon one's healing ability and degree and chronicity of injury. Most people may only need a few treatments while others may need 10 or more depending on the degree and chronicity of injury. The average number of treatments is 3-6 for an area treated. The best thing to do is get an evaluation to see if you are an appropriate candidate. Once you begin treatment, you will understand how you are responding.  To book an appointment for your evaluation contact the clinic directly.

Are you a candidate for Prolotherapy?
Any joint in the body can be treated successfully with prolotherapy. A simple "self diagnosis" for back pain would be to consider if you have the "theatre, cocktail party syndrome".  Your back, leg, neck or other pain is worse when standing still, like at a cocktail party. When you go to sit down, there is some relief but if you sit for too long, like being at the theatre, the pain returns.  When you wake up in the morning the pain is worse, and only relieved with movement.  There may only be relief as long as you are active, returning once you rest.  This is because when you are at rest, the muscles relax and it is the ligaments that are supporting the structure. If the ligaments are lax, then you are more susceptible to pain.  Also passive stretching of ligaments or firm pressure on ligament sites may also be indications for prolotherapy.  Of course, only a physician trained in prolotherapy can determine whether your condition would benefit from it or another method of treatment.

For more on Prolotherapy, Regenerative Injection Therapy click here for page 2

For more on PRP Regenerative Injection Therapy

Patient Testimonials

The Ligament Injury-Osteoarthritis Connection: The Role of Prolotherapy in Ligament Repair and the Prevention of Osteoarthritis:

Prolotherapy is a decades-old, well-documented procedure that stimulates the body’s naturally-occurring healing processes to produce more collagen within injured joint ligaments, providing increased stability, decreased pain and improved function. This article reviews the physiology of ligaments and damage sustained due to injury, the body’s response to injury, and the process of ligament repair, as well as degenerative changes and dysfunction that occur when full restoration of ligament function is not achieved.